Search results for " anidulafungin"

showing 2 items of 2 documents

Evaluation of the Disk Diffusion Method Compared to the Microdilution Method in Susceptibility Testing of Anidulafungin against Filamentous Fungi

2008

ABSTRACT Susceptibility testing of anidulafungin (AFG) against 32 mold isolates showed an excellent correlation between disk diffusion (DD) and broth microdilution methods. Based on our data, a 2-μg disk of AFG and a 24-h reading time might represent the best parameters for AFG DD testing against filamentous fungi.

Microbiology (medical)Susceptibility testingAntifungal AgentsDisk Diffusion; Yeasts; CaspofunginDisk diffusion anidulafungin MIC MECMycologyMicrobial Sensitivity TestsBiologyAnidulafunginSettore MED/42 - Igiene Generale E ApplicataDisk DiffusionMicrobiologyEchinocandinsCaspofunginYeastsmedicineHumansAgar diffusion testFood scienceAspergillus Anidulafungin Disk Diffusion1 3 β glucan synthaseAnidulafungineBroth microdilutionFungiAnidulafunginaMycosesAnidulafunginmedicine.drugJournal of Clinical Microbiology
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Anidulafungin in combination with amphotericin B against Aspergillus fumigatus.

2009

ABSTRACT We investigated the effects of anidulafungin alone and in combination with amphotericin B against Aspergillus fumigatus . Indifference was the only type of interaction observed in vitro. Anidulafungin at 1 and 5 mg/kg of body weight/day, amphotericin B at 1 mg/kg/day, and combination therapy prolonged the survival of mice with invasive aspergillosis. Anidulafungin at 5 mg/kg/day, alone and in combination with amphotericin B, reduced the kidney fungal burden. Overall, the combination was not superior to the most active single drug.

Settore MED/07 - Microbiologia E Microbiologia ClinicaAntifungal AgentsCombination therapymedicine.drug_classAntibioticsMicrobial Sensitivity TestsPharmacologyAspergillosisAnidulafunginKidneyAspergillus fumigatusMicrobiologyEchinocandinsMicePharmacotherapyAmphotericin BAmphotericin BmedicineAnimalsAspergillosisPharmacology (medical)Experimental TherapeuticsPharmacologyAspergillusbiologyAspergillus fumigatusaspergillus anidulafungin amphotericin BBrainbiology.organism_classificationmedicine.diseasebacterial infections and mycosesInfectious DiseasesAnidulafunginDrug Therapy Combinationmedicine.drugAntimicrobial agents and chemotherapy
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